Abstract: An experiment of water-rock interaction in the packed bed reactor between granodiorite and pure water under the condition of stable pressure of 22 MPa and continuous current has been performed to study the formation process of the Hucun skarn copper deposit in Tongling, Anhui. The experimental results show that the rates of waterrock interaction are inversely correlated to the velocity of water flow and positively correlatied to the residence time of the water in the system. These results may explain distribution of the copper, molybdenum etc. mineralizations around the pluton. It is inferred that the copper in the ore-forming fluid might be transferred in a supercritical state and be separated out under the critical state. The leaching of copper from the rock is difficult at low temperatures.The experiment indicats that the dissolution rates of copper, zinc and other ore-forming elements are different under the same temperatures, which might be one of reasons for zoning of the ore-forming elements.