Abstract: Fluorine contents in grains of Xuzhou epidemic fluorosis area range between 0.70 and 0.85 mg/kg，and don’t exceed the national hygienic standard values. Fluorine contents in various main vegetables are from 1.88 to 12.25 mg/kg，among which green vegetable has the highest fluorine content of 12.25 mg/kg They are much higher than the national hygienic standard values Fluorine in vegetable leaves is higher than that in tubers and seeds of the same vegetables. Fluorine contents in different tree leaves are up to 24.56- 34.29 mg/kg The correlation analysis demonstrates that fluorine in plants mainly comes from water-soluble fluorine in soil Leaf vegetables(green vegetable and cabbage)and tree leaves have much higher water-soluble fluorine content than that in soil. It shows that fluorine has a trend to be accumulated in leaves and is transported in aqueous solution The main food，grains，is not harmful to human health in Xuzhou epidemic fluorosis area High fluorine content in main vegetables is one of the key factors to cause epidemic fluorosis