Abstract: The deep-well injection of industrial waste is an effective waste disposal method. In China, with increasing understanding and continuous improvement of technology, it will be an important choice for the final disposal of waste, which may be highly toxic or difficult to deal with. SWIFT is a fully transient, three-dimensional model which can simulate the flow and transport of fluid, heat (energy), brine, and radionuclide chains in porous and fractured geologic media. The model is able to take full account of the deep geological environment of the injection zone, which is often under high temperature and pressure.Besides the application in the underground injection, it also can be used to simulate and analyze the seawater intrusion, high-level radioactive nuclear waste isolation and so on. In the United States, SWIFT model has been employed to predict the waste transport in many underground injection projects. This paper gives a comprehensive presentation of this model, and put forward several issues which should be paid particular attention to during usage.