Abstract: The paper focuses on the systematic study of two typical ductile shear zones in median- deep levels from the southern part of Tancheng-Lujiang fault belt. The influence and restrain on the chemical component migration and activation in the rocks by ductile deformation have been revealed. On the basis of simulant calculation of the migration of active component in the rocks, the authors have established the chemical reaction equations of different metamorphic rock pairs，The paper also discusses the important role played by fluids in the mylonitization.