Abstract: In this paper the forms of existence and distribution regularities of gold in Yueshan Cu-Mo ore deposit, Anqing, western Anhui Province, are studied by means of optical microscope, chemical analysis, electron microprobe, and proton and nuclear microprobes in PIXE system etc. It shows that the gold in the copper deposit mainly occurs in micro-grained native gold of independent minerals including silver-bearing gold, silver gold and natural gold, which are concentrated in quartz vein type copper ore, copper-bearing calcite veins and diorite type copper ore. They’are associated with chalcopyrite, pyrite, bornite, molybdenite and quartz. The gold-silver mineral series is mainly composed of native gold, whose grains range from 0.15to 0.30 mm, with a maximum size of more than 0.5 mm. The intensity of gold mineralization varies with the depth of the ore body; the gold grade in the upper part is higher than that of the lower, whereas the degree of variation of gold grade in the horizontal direction is less than in the vertical direction. This study provides an evidence for the comprehensive use of the accompanying gold in the Cu-Mo ore deposit in this region.